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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 50-year-old patient presents to the physician complaining of anxiety, insomnia, a depressed mood, and decreased energy level. Paroxetine therapy is initiated. Which symptom will be the last to respond?

A) Anxiety
B) Decreased energy
C) Insomnia
D) Depressed mood

2. A patient with rheumatoid arthritis has been experiencing increased pain over the last 2-3 weeks. The patient's rheumatoid arthritis has previously been controlled with methotrexate and periodic NSAID and steroid use for acute flares. However, currently this regimen is inadequate.
The physician wants to initiate therapy with etanercept.
Which of the following infections should be screened for prior to initiating therapy?

A) Candida
B) Hepatitis A
C) Legionella
D) Tuberculosis

3. Post myocardial infarction, a patient's cardiac profile and serum chemistry results show the following values:
Heart rate: 120 bpm
Blood pressure: 80/40 mm Hg
Pulmonary capillary Wedge pressure: 6 mm Hg
Right atrial pressure: 2 mm Hg
Cardiac index: 2.3 L/min/m2
Sodium: 136 mEq/L
Potassium: 4.2 mEq/L
Chloride: 98 mEq/L
Bicarbonate: 22 mEq/L
Blood urea nitrogen: 25 mg/dL
Creatinine: 1.0 mg/dL
Glucose: 110 mg/dL
Which one of the following therapeutic regimens is most appropriate for the initial treatment of this patient?

A) Normal saline 500 mL/h
B) Dopamine 15 mcg/kg/min
C) Nitroprusside 2 mcg/kg/min
D) Furosemide 40 mg intravenous push

4. A 69-year-old Woman with chronic liver disease treated with furosemide and potassium chloride for ascites and peripheral edema presents with weakness and fatigue. Her serum laboratory Values are:
* Sodium: 138 mEq/L
* Potassium: 2.6 mEq/L
* Glucose: 88 mg/dL
* BUN: 33 mg/dL
* Chloride: 101 mEq/L
* HCO3- 26 mEq/L
* Creatinine: 1.1 mg/dL
Attempts to increase her serum potassium over the next 48 hours include intravenous replacement (240 mEq over this period), without success. The current serum potassium concentration is 2.8 mEq/L. Which of the following is the most appropriate test to obtain for this patient?

A) Urinary sodium
B) Urinary potassium
C) Serum antidiuretic hormone
D) Serum magnesium

5. A 47-year-old patient with cirrhosis, ascites, and acute renal failure presents to the emergency department. A peritoneal tap reveals spontaneous bacterial peritonitis (neutrophils = 789 in the ascitic fluid). Medical history includes ethanol abuse and positivity for HCV antibody. What is the most appropriate drug therapy for this patient?

A) Cefotaxime with albumin
B) Piperacillin/tazobactam with dextran 40
C) Levofloxacin With dextran 40
D) Gentamicin With albumin

Solutions: